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Carbohydrates are the most abundant organic molecules found in nature, serving as vital components in various biological processes. At Sapala, we excel in preparing protected carbohydrates that act as chiral building blocks for chiral pool synthesis, transforming these building blocks into important enantiopure molecules.
Oligosaccharides are short chains of monosaccharides, typically consisting of 2 to 10 simple sugars. They play essential roles in cell recognition and binding, with glycolipids being crucial in immune responses. Our team at Sapala has extensive experience in this area, successfully synthesizing compounds like Leptosine efficiently.
Orthogonally protected carbohydrate molecules serve as versatile chiral building blocks that can be converted into a diverse range of structurally complex molecules. Sapala boasts a wealth of experience in creating various carbohydrate building blocks, including fluorinated and cyclopentanoid derivatives.
Glycosylation is a critical step in synthesizing nucleosides and oligosaccharides. At Sapala, we have successfully demonstrated glycosylation on structurally intriguing carbohydrate building blocks to produce advanced compounds like LNA, BNA, and acyclic nucleosides. Our expertise ensures precision in crafting these essential structures for pharmaceutical applications.
